McLeod et al identified inappropriate prescription practices for older adults in Canada. Certain prescriptions should be avoided in patients with cardiovascular disease. The authors are from McGill University in Montreal.
Disorder |
Drug |
Comorbid |
Reason |
hypertension |
beta-adrenergic blocker |
asthma or COPD |
worsen asthma or COPD |
angina |
beta-adrenergic blocker |
asthma, COPD, heart failure |
worsen asthma, COPD or heart failure |
hypertension |
reserpine |
|
depression and extrapyramidal effects |
atrial fibrillation |
disopyramide |
|
anticholinergic side effects, sudden death |
hypertension |
thiazide |
gout |
worsen gout |
hypertension |
calcium channel blocker |
heart failure |
worsen heart failure |
hypertension |
beta-adrenergic blocker |
heart failure |
worsen heart failure |
angina |
beta-adrenergic blocker, long term |
Raynaud |
worsen Raynaud |
hypertension |
beta-adrenergic blocker, long term |
Raynaud |
worsen Raynaud |
Specialty: Pharmacology, clinical