McLeod et al identified inappropriate prescription practices for older adults in Canada. Certain prescriptions should be avoided in patients requiring analgesia. The authors are from McGill University in Montreal.
|
Disorder |
Drug |
Comorbid |
Reason |
|
gout |
indomethacin |
|
gastropathy, salt and water retention, neurological side effects |
|
osteoarthritis |
NSAID |
warfarin |
bleeding |
|
osteoarthritis |
NSAID |
heart failure |
worsen heart failure, salt and water retention |
|
osteoarthritis |
NSAID, long term |
peptic ulcer |
recurrent peptic ulcer |
|
osteoarthritis |
NSAID, long term |
chronic renal failure |
worsen renal failure, salt and water retention |
|
osteoarthritis |
NSAIDS, long term |
|
gastropathy, bleeding, salt and water retention
|
|
osteoathritis |
phenylbutazone |
|
bone marrow depression |
|
pain |
ASA |
warfarin |
bleeding |
|
pain |
certain NSAIDs (ketorolac, mefenamic acid, piroxicam) |
|
upper GI bleeding |
|
pain |
meperedine |
|
falls, confusion, dependency |
|
pain |
NSAIDS, long term |
hypertension |
worsen hypertension, salt and water retention |
|
pain |
pentazocine |
|
falls, confusion, dependency |
Specialty: Pharmacology, clinical
