Mahoney and Shapshay graded the response to laser therapy for epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT). This can help to compare the effectiveness of various therapies. The authors are from Boston University Medical Center.


Therapeutic modality: Nd:YAG laser


Criteria for good response:

(1) > 50% reduction in severity

(2) > 50% reduction in frequency

(3) for >= 6 months


If the effects lasted for < 6 months then the response was considered poor. Presumably no change or worsening of severity and frequency would also be considered poor response.


There are several ways to measure outcomes:

(1) VAS scales from 0 to 10 cm before and after

(2) number of nosebleeds per week before and after

(3) reduction in severity grade


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