NOTE: The Bladder Pain Syndrome is a term that replaces Interstitial Cystitis (IC) according to the recommendations of the European Society for the Study of Bladder Pain Syndrome/Interstitial Cystitis (ESSIC).
Parameters:
(1) clinical and cystoscopic score
(2) number of mast cells in a detrusor muscle biopsy cut 3 microns thick and stained using the tryptase method
Clinical and cystoscopic score components:
(1) bladder pain
(2) nocturia
(3) bladder capacity < 500 mL
(4) petechial hemorrhage in the bladder mucosa
(5) fibrosis in the bladder wall
|
Response
|
Points
|
|
no
|
0
|
|
yes
|
1
|
total score =
= SUM(points for all 5 parameters)
The number of mast cells was counted per square mm in biopsies from the detrusor muscle sectioned with a thickness of 3 microns and stained using the tryptase method.
A mast cell count >= 27 per square mm indicates mastocytosis.
According to Figure 1c page 206 a clinical/cystoscopic score of 3 roughly corresponds to a mast cell count of 27 per square mm.
