Description

Kitamura et al evaluated patients with infections of aortic grafts or aneurysms. Making the diagnosis of an aortic infection can be difficult if the findings are subtle or nonspecific. The authors are from the University of Tokyo.


 

Criteria for active infection:

(1) clinical findings of infection (see below)

(2) operative findings of infection

(3) positive culture (from graft, the aortic wall, periarotic abscess)

 

Criteria for culture-negative infection:

(1) pre-operative antibiotic therapy

(2) clinical findings of infection

(3) operative findings of infection ("dirty" graft, purulent fluid, eccentric aneurysm)

(4) positive blood culture or serologic evidence of syphilis

(5) pathologic findings (neutrophilic infiltrate with or without necrosis)

 

Clinical findings of infection:

(1) fever > 37.5°C

(2) leukocytosis > 10,000 per µL

(3) increased serum C-reactive protein (CRP)

(4) pain or discomfort

(5) wound infection following aortic surgery

 

Imaging findings on CT or MRI scan may include:

(1) enlarging periaortic abscess

(2) graft-enteric erosions

(3) periaortic fluid with bubbles

(4) enlarging pseudoaneurysm

(5) aortoesophageal fistula

 


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