Kahn and Appleboom reported criteria for Mixed Connective Tissue Disease (MCTD).
Parameters:
(1) serological criteria
(2) Raynaud's phenomenon
(3) additional clinical criteria
Serological criteria: high titer (>= 1:2000) anti-RNP antibody (speckled ANA, anti-U1 RNP))
Additional clinical criteria:
(1) synovitis
(2) myositis
(3) swollen fingers
Criteria for MCTD - all of the following:
(3) at least 2 of the additional clinical criteria
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Specialty: Immunology/Rheumatology
