Patient selection:
(1) evaluated within 6 hours of symptom onset
(2) ST-segment elevation >= 0.1 mV in at least 2 limb leads OR >= 0.2 mV in at least 2 contiguous precordial leads
(3) >= 18 years of age
(4) exclusion: bundle branch block, therapy with GP2b/3a antagonist in previous 12 hours, recent stroke or recent transient ischemic attack (TIA)
Patients were treated with alteplase with dalteparin
Parameters:
(1) ST segment height in the lead with the highest initial ST elevation, in mV
(2) ST segment height in that lead at 60 minutes, in mV
(3) ST segment height in that lead at 90 minutes, in mV
percent resolution at 60 minutes =
= ((initial height) - (height at 60 minutes)) / (initial height) * 100%
percent resolution at 90 minutes =
= ((initial height) - (height at 90 minutes)) / (initial height) * 100%
|
Time Frame
|
Percent Resolution
|
30-day Mortality
|
|
60 minutes
|
< 50%
|
6.1%
|
|
60 minutes
|
>= 50%
|
1.4%
|
|
90 minutes
|
< 30%
|
8.4%
|
|
90 minutes
|
30 to 69%
|
3.9%
|
|
90 minutes
|
>= 70%
|
1.8%
|
