Jass et al published a working definition to identify patients with familial juvenile polyposis in 1988.


Criteria for familial juvenile polyposis - one or more of the following:

(1) more than 5 juvenile polyps of the colorectum

(2) juvenile polyps throughout the gastrointestinal tract (stomach, small intestine, colon and rectum)

(3) any number (>=1) of juvenile polyps in a patient with a family history of juvenile polyposis


Syndromes of familial juvenile polyposis:

(1) juvenile polyposis of infancy (transmitted as non-sex-linked recessive trait)

(2) familial juvenile polyposis coli (autosomal dominant trait with high penetrance)

(3) familial juvenile gastric polyposis

(4) generalized juvenile polyposis

Polyp(s) Located in

Family History

Juvenile Polyposis (JP)

colon and rectum


solitary JP

colon and rectum, variable small intestine


JP coli

entire GI tract (from stomch to rectum)


juvenile gastrointestinal polyposis



familial JP of stomach


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