Criteria of Hughes at al for Providing Additional Therapy to a Woman with Ductal Carcinoma in Situ (DCIS)

 

Patient selection: female with ductal carcinoma in situ in a breast biopsy without infiltrative carcinoma

 

All women were offered tamoxifen therapy for 5 years.

 

Criteria for a woman with DCIS who may not require additional therapy:

(1) tumor size <= 2.5 cm

(2) absence of residual calcifications following surgery

(3) narrowest surgical margn >= 3 mm

(4) Grade 1 or 2 (low or intermediate grade) nuclei

 

Additional therapy may include:

(1) radiation therapy

(2) surgical re-excision

 

Women with DCIS who met the criteria and who did not undergo irradiation had an ipsilateral recurrence rate of 6%.