Portopulmonary hypertension can be diagnosed in a patient with portal hypertension if certain criteria are met.
Alternative terms: pulmonary arterial hypertension associated with liver disease; pulmonary arterial hypertension associated with portal hypertension
Criteria for diagnosis:
(1) presence of portal hypertension
(2) raised mean pulmonary arterial pressure (> 25 mm Hg at rest; > 30 mm Hg during exercise)
(3) increased pulmonary vascular resistance (> 240 dynes per second • cm^(-5))
(4) left ventricular end-diastolic pressure < 15 mm Hg
(5) exclusion of other causes of pulmonary hypertension (valvular heart disease, left-sided heart disease, interstitial lung disease, sleep-related breathing disorders, chronic thromboembolism)
where:
• In the footnote to the table on page 1463 the author mentions that some clinicians define an increased pulmonary vascular resistance in patients with portal hypertension as > 120 dynes per second • cm^(-5).
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