Portopulmonary hypertension can be diagnosed in a patient with portal hypertension if certain criteria are met.


Alternative terms: pulmonary arterial hypertension associated with liver disease; pulmonary arterial hypertension associated with portal hypertension


Criteria for diagnosis:

(1) presence of portal hypertension

(2) raised mean pulmonary arterial pressure (> 25 mm Hg at rest; > 30 mm Hg during exercise)

(3) increased pulmonary vascular resistance (> 240 dynes per second • cm^(-5))

(4) left ventricular end-diastolic pressure < 15 mm Hg

(5) exclusion of other causes of pulmonary hypertension (valvular heart disease, left-sided heart disease, interstitial lung disease, sleep-related breathing disorders, chronic thromboembolism)



• In the footnote to the table on page 1463 the author mentions that some clinicians define an increased pulmonary vascular resistance in patients with portal hypertension as > 120 dynes per second • cm^(-5).


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