Criteria of Higgins et al for Bronchopulmonary Dysplasia (BPD) Severity Reported for a 2018 NICHD Workshop

Description

Higgins et al reported criteria for grading the severity of Bronchopulmonary Dysplasia (BPD) at a NICHD workshop.

Selection criteria:

(1) premature infant (born < 32 weeks gestation)

(2) bronchopulmonary dysplasia

(3) persistent parenchymal lung disease with radiographic confirmation

Criterion for grading: Oxygen use at 36 weeks postmenstrual age (PMA) with oxygen delivery FIO2 given for >= 3 consecutive days to maintain arterial oxygen saturation in the 90-95%

Modalities and FIO2:

(1) invasive positive pressure ventilation (IPPV)

(2) N-CPAP

(3) noninvasive positive pressure ventilation (NIPPV)

(4) nasal cannula

(5) hood oxygen

Modality	Other	FIO2	Grade
IPPV		21 (room air)	II
		> 21	III
N-CPAP		21	I
		22-29	II
		>= 30	III
NIPPV		21	I
		22-29	II
		>= 30	III
nasal cannula	1 to 2.99 L/min	22-29	I
	1 to 2.99 L/min	>= 30	II
	>= 3 L/min	21	I
	>= 3 L/min	22-29	II
	>= 3 L/min	>= 30	III
	< 1 L/min	22-70	I
	< 1 L/min	> 70	II
hood oxygen		22-29	I
		>= 30	II

Grade III(A) designates early death (between 14 days of postnatal age and 36 weeks PMA) owing to persistent parenchymal lung disease and respiratory failure not attributable to another cause.

To read more or access our algorithms and calculators, please log in or register.