Herbort et al reported criteria for the diagnosis of ocular sarcoidosis formulated at the First International Workshop on Ocular Sarcoidosis (IWOS). The authors are from multiple institutions from around the world.
Patient selection: possible ocular sarcoidosis (OS)
The criteria may be used for localized ocular involvement or part of systemic disease.
Parameters:
(1) biopsy consistent with sarcoidosis (noncaseating granulomas)
(2) compatible uveitis
(3) bilateral hilar lymphadenopathy (BHL)
(4) suggestive intraocular signs (out of 7)
(5) positive investigational tests (out of 5)
(6) other possible causes of uveitis (tuberculosis, etc) ruled out
Parameter
Definite OS
Presumed OS
Probable OS
Possible OS
biopsy
supportive
not done
not done
negative
uveitis
present
present
NA
NA
BHL
NA
present
negative
NA
intraocular signs
NA
NA
>= 3
>= 4
positive tests
NA
NA
>= 2
>= 2
exclusion
Yes
Yes
Yes
Yes
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