Criteria of Hanifin and Rajka for the Diagnosis of Atopic Dermatitis

Age of patient

• pruritis?

• facial and extensor involvement?

• flexural lichenification or linearity?

• chronic or chronically-relapsing dermatitis?

• personal history of atopy (asthma, allergic rhinitis, atopic dermatitis)?

• family history of atopy (asthma, allergic rhinitis, atopic dermatitis)?

• xerosis?

• ichthyosis, palmar hyperlinearity or keratosis pilaris?

• immediate (type 1) skin test reactivity?

• increased serum IgE levels?

• early age of onset?

• tendency for cutaneous infections (Staph. aureus, Herpes simplex) or impaired cell-mediated immunity?

• tendency toward nonspecific hand or foot dermatitis?

• nipple eczema?

• cheilitis?

• recurrent conjunctivitis?

• Dennie-Morgan infra-orbital fold?

• keratoconus?

• anterior subcapsular cataracts?

• orbital darkening?

• facial pallor or facial erythema?

• pityriasis alba?

• anterior neck folds?

• itch when sweating?

• intolerance to wool and lipid solvents?

• perifollicular accentuation?

• food intolerance?

• course influenced by environmental or emotional factors?

• white dermographism or delayed blanch?