Graus et al reported a number of criteria applicable to the diagnosis of autoimmune encephalitis. One criterion screens a patient for possible autoimmune encephalitis. The authors are from multiple institutions from around the world.

Patient selection: possible autoimmune encephalitis


Criteria for possible autoimmune encephalitis - all of the following:

(1) subacute onset (less than 3 months)

(2) one or more of the following:

(2a) new focal CNS finding

(2b) seizures not explained by previously known seizure disorder

(2c) CSF white blood cell count > 5 per microliter

(2d) MRI scan suggestive of encephalitis

(3) reasonable exclusion of alternative diagnoses



• The onset may include: short-term memory loss, altered mental status, psychiatric symptoms.

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