deShazo et al listed criteria for diagnosing sarcoidosis of the sinuses. The authors are from the University of Mississippi in Jackson.
Patient selection: chronic sinusitis
(1) evidence of sinusitis on imaging studies
(2) biopsy evidence of noncaseating granulomas
(3) negative for acid fast bacilli and fungi (paper refers to stains but culture would provide additional evidence)
(4) negative for serologic tests for syphilis and for ANCA
(5) exclusion of other disorders causing granulomatous inflammation
Additional reasons to consider sarcoidosis:
(1) presence of sarcoidosis elsewhere
(2) presence of diffuse polyposis
(3) presence of an elevated serum ACE (although this may not be specific)
(4) failure to respond to usual therapy
To read more or access our algorithms and calculators, please log in or register.
Specialty: Otolaryngology, Infectious Diseases, Immunology/Rheumatology