Colmenero et al listed criteria for therapeutic failure in a patient with brucellosis. The authors are from Carlos Haya University Hospital in Malaga, Spain.
Assessment: after 1 month of antibiotic treatment with good adherence
Parameters:
(1) clinical symptoms
(2) laboratory marker of inflammation (C reactive protein or erythrocyte sedimentation rate)
(3) imaging findings
(4) culture
Symptoms
Laboratory Marker
Imaging Findings
Cultures
Interpretation
none
normal
normal
negative
complete response
none or reduced
normal to reduced
normal to reduced
negative
partial response
persistent or worsening
unchanged to increased
unchanged or worsening
negative or positive
failure
where:
• The paper describes therapeutic failure. The other categories were added.
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