Coleman et al listed criteria for diagnosing pulmonary involvement in a patient with secondary syphilis. The authors are from the University of California at San Francisco.
Criteria for the diagnosis of pulmonary involvement in secondary syphilis:
(1) The patient has a clinical history and physical findings consistent with secondary syphilis.
(2) Serologic testing is positive for antitreponemal antibodies.
(3) Pulmonary nodules or other lesions are seen on imaging studies with or without pulmonary signs and symptoms.
(4) There is no other diagnoses that can explain the pulmonary disease.
(5) The patient shows a positive therapeutic response to syphilis therapy.
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