Description

Braun et al listed criteria for an adequate therapeutic trial of an NSAID in patients with ankylosing spondylitis. The authors are involved in the ASAS (Assessment in Ankylosing Spondylitis) Working Group.


 

Patient selection: ankylosing spondylitis

 

Drug: non-steroidal anti-inflammatory drug (NSAID)

 

Parameters:

(1) duration of trial therapy

(2) dose

(3) contraindications, intolerance or complications (discontinuation for problems)

Duration of Therapy

Dose

Discontinuation

Criteria

>= 3 months

maximum recommended or tolerated

No

1

>= 3 months

maximum recommended or tolerated

Yes

2

> 0 and < 3 months

maximum recommended or tolerated

Yes

3

 

where:

• Not using an NSAID initially because of contraindication(s) probably should not be counted as a therapeutic trial.

 


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