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Criteria for the Intraoperative Floppy Iris Syndrome (IFIS) Associated with Alpha-1 Antagonist Therapy (Tamsulosin, Flomax)

Specialty:

Neurology, Psychiatry, Ophthalmology & Otolaryngology
Clinical Pharmacology & Toxicology

Objective:

ICD-10:

Description:

A small percentage of patients taking the alpha-1 antagonist drug tamsulosin (Flomax) may develop an abnormality of the iris that becomes evident during ocular surgery. In theory the risk should extend to similar medications. It may be associated with surgical complications if the ophthalmologist is caught unawares; these problems can be avoided if it is anticipated and a suitable operative technique is used.

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