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Criteria for the Diagnosis of the Serotonin Syndrome

Specialty:

Psychiatry

Objective:

ICD-10:

Description:

The serotonin syndrome, also referred to as the toxic serotonin syndrome (TSS) is a symptom complex caused by an increase in the biologic activity of serotonin. It most often occurs in patients being treated concurrently with 2 or more drugs that increase brainstem serotonin activity or stimulate serotonin receptors. It is associated with several of the medications used to treat depression or other psychiatric conditions, and it has been noticed more often since the introduction of the selective serotonin reuptake inhibitors (SSRI).

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