Familial inflammatory dilated cardiomyopathy may be diagnosed if certain findings are present.
Patient selection: not specified but presumably has evidence of inflammatory cardiomyopathy
Criteria for the diagnosis - >= 1 first degree relative with >= 1 of the following:
(1) diagnosis of inflammatory cardiomyopathy has been established
(2) unexplained sudden death or stroke before the age of 50
(3) major and/or minor echocardiographic or electrocardiographic criteria met (see table)
where:
• Criterion 2 would seem to have false positives.
Major criteria:
(1) left ventricular end-diastolic diameter (LVEDD) >= 117% of predicted
(2) fractional shortening (FS) < 25%
Minor criteria:
(1) LVEDD 113 to 116% of predicted
(2) FS 25 to 27%
(3) pericardial effusion
(4) unexplained conduction defect (second or third degree AV block, bundle branch block) or unexplained supraventricular arrhythmia before the age of 50 years
|
Major Criteria
|
Minor Criteria
|
Status
|
|
2
|
NA
|
affected
|
|
1
|
>=1
|
affected
|
|
0
|
>=3
|
affected
|
|
1
|
0
|
possibly affected
|
|
0
|
1 or 2
|
possible affected
|
|
0
|
0
|
unaffected
|
