Some renal allografts may be suboptimal for transplantation. This may be due to features of the donors or factors surrounding the organ collection.


Criteria for donors likely to provide a suboptimal kidney for transplantation:

(1) age < 14 or > 65 years of age (extremes)

(2) diabetes mellitus

(3) hypertensive

(4) impaired renal function

(5) primary brain tumors

(6) prolonged hypotension or poor cardiovascular status

(7) primary renal disease


Criteria for suboptimal handling of allografts:

(1) prolonged cold or warm ischemia

(2) technical problems with organ retrieval (vascular injury, etc.)

(3) unfavorable findings on pretransplant biopsy


The presence of one or more of these risk factors may indicate an allograft that will function suboptimally.


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