Criteria for the diagnosis of Henoch-Schonlein purpura were proposed at an International Consensus Conference held at the University of North Carolina, Chapel Hill, North Carolina.
Lesion: vasculitis affecting small blood vessels
Vessel
Involvement
venules
yes
capillaries
arterioles
small arteries
possibly
medium-sized arteries
no
large arteries
Features:
(1) IgA immune deposits
(2) presence of arthralgias and/or arthritis
(3) glomerulonephritis
(4) skin involvement
(5) GI tract involvement
Differential diagnosis:
(1) cryoglobulinemic vasculitis - cryoglobulin deposits
(2) microscopic polyangiitis - no or rare immune deposits
(3) serum sickness
(4) SLE
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Purpose: To evaluate a patient with a vasculitis for features of Henoch-Schonlein purpura.
Specialty: Immunology/Rheumatology
Objective: criteria for diagnosis
ICD-10: D69.0,
