Criteria for Definitive Diagnosis - one of the following:
(1) direct microscopic identification of T. pallidum in lesion material
(2) direct microscopic identification of T. pallidum in lymph node aspirate
(3) direct microscopic identification of T. pallidum in biopsy section
Criteria for Presumptive Diagnosis:
(1) skin or mucous membrane lesions typical of secondary syphilis
(1a) macular, papular, follicular, papulosquamous or pustular
(1b) condylomata lata (anogenital region or mouth)
(1c) mucous patches (oropharynx, cervix)
AND
(2) one or both of the following
(2a) reactive nontreponemal test titer of >= 1:8 and no previous history of syphilis
(2b) for patients with a history of syphilis, a fourfold increase in most recent quantitative nontreponemal test titer compared with results of past tests
Criteria for Suggestive Diagnosis:
(1) presence of clinical manifestations
AND
(2) sexual exposure within past 6 months to a person with early syphilis
AND
(3) serological test results are not available
