Criteria for Definitive Diagnosis - one of the following:
(1) direct microscopic identification of T. pallidum in lesion material
(2) direct microscopic identification of T. pallidum in lymph node aspirate
(3) direct microscopic identification of T. pallidum in biopsy section
Criteria for Presumptive Diagnosis:
(1) typical chancre
AND
(2) one or both of the following:
(2a) reactive nontreponemal test and no history of syphilis
(2b) for patients with a history of syphilis, a fourfold increase in most recent quantitative nontreponemal test titer compared with results of past tests
Criteria for Suggestive Diagnosis:
(1) lesion resembling a chancre
AND
(2) sexual contact within the preceding 90 days with a person who has primary, secondary or early latent syphilis