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Converting Between Serial Dilution and ELISA Units for Anti-Nuclear Antibodies (ANA)

Specialty:

General content (available to all)

Objective:

ICD-10:

Description:

Historically measurement of antinuclear antibodies (ANA) was done by indirect immunofluorescence using serial dilutions of patient serum. ELISA testing offers many advantages and is becoming more widely used. A clinician may need to evaluate a patient with results from both types of testing, both of which differ in their units of reporting.

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