Le Deley et al used conversion factors for comparing doses of anthracyclines in patients undergoing chemotherapy for solid tumors. The authors are from the Societe Francaise d'Oncologie Pediatrique.
Reference drug: doxorubicin
Reference dose: 50 mg per square meter BSA
Anthracycline
Dose Equivalent to 50 mg per square meter doxorubicin
daunorubicin
60 mg per square meter
epirubicin
75 mg per square meter
mitoxantrone
12.5 g per square meter
zorubicin
100 mg per square meter
where:
• Mitoxantrone is an anthracedione which the authors included with the anthracyclines.
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