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Contraindications to the Use of Recombinant Protein C

Description:

Recombinant human activated protein C is a natural anticoagulant that may have some benefit for patients with severe sepsis. A serious side effect of therapy is the occurrence of severe bleeding. Certain conditions may contraindicate therapy because of the high risk of life threatening hemorrhage, although this must be balanced against the poor prognosis of overwhelming sepsis.

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