The presence of certain conditions may preclude the use of aspirin as an antiplatelet agent. An alternative antiplatelet, anti-inflammatory or antipyretic agent must be used if one of these conditions is present.


Contraindications to aspirin therapy:

(1) hypersensitivity to aspirin or salicylates, especially a history of bronchospasm or an anaphylactic reaction

(2) hereditary or acquired bleeding disorder

(2a) hemophilia

(2b) von Willbrand's disease with bleeding

(2c) other hypocoagulable state

(3) active bleeding

(3a) bleeding peptic ulcer

(3b) intracranial bleeding

(4) child with viral illness (due to risk of Reye's syndrome)


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