A patient with Turner Syndrome usually has a short stature that is responsive to therapy with growth hormone. Therapy with growth hormone has a number of other consequences for the patient.

Indication for growth hormone therapy: child whose height is less than 5% for age


Therapy with growth hormone may expose underlying scoliosis, which needs to be identified and corrected.


Adverse effects of growth hormone therapy:

(1) intracranial hypertension

(2) slipped capital femoral epiphyses

(3) pancreatitis


Problems in patients with Turner Syndrome probably unrelated to growth hormone therapy:

(1) osteoporosis

(2) aortic dissection or rupture


Additional problems may arise if:

(1) the start of growth hormone therapy is delayed

(2) it is given for too long.

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