The American College of Cardiology (ACC) and the American Heart Association (AHA) developed criteria for identifying a patient with heart failure who is a candidate for cardiac transplantation. A patient who does not meet one or more of these criteria has an insufficient indication for transplantation.
Patient selection: presence of heart failure
Condition |
Transplant |
refractory cardiogenic shock |
absolute indication |
dependence on intravenous inotropic support to maintain adequate organ perfusion |
absolute indication |
peak VO2 <= 10 mL per kg per minute, with anaerobic metabolism |
absolute indication |
peak VO2 11-14 mL per kg per minute, with major restrictions on the activities of daily living |
relative indication |
severe symptoms of cardiac ischemia with major restrictions in activities of daily living, not amenable to coronary artery bypass surgery (CABG) or percutaneous coronary intervention (PCI) |
absolute indication |
recurrent unstable ischemia/angina, not amenable to coronary artery bypass surgery (CABG) or percutaneous coronary intervention (PCI) |
relative indication |
recurrent symptomatic ventricular arrhythmias refractory to all therapeutic modalities |
absolute indication |
recurrent instability of fluid balance and/or renal function not due to patient noncompliance with medical regimens |
relative indication |
where:
• Peak VO2 = maximal oxygen uptake in mL per kg per minute.
• Cardiac ischemia or angina amenable to coronary artery bypass surgery (CABG) or percutaneous coronary intervention (PCI) should undergo those procedures.
• Problems with fluid balance or renal function related to noncompliance are better addressed by trying to improve compliance. A patient who is noncompliant with medical regimens is unlikely to make a good candidate for cardiac transplant.
Purpose: To determine if a patient with heart failure is a candidate for cardiac transplantation.
Specialty: Cardiology, Surgery, general
Objective: selection, failure handling and therapy escalation, response to therapy
ICD-10: I50,