Conditions (other than PG) that can cause cutaneous ulcers include:
(1) vasculitis
(2) vascular occlusions
(3) skin involvement in hematologic malignancies
(4) skin infection
(5) drug-induced skin ulcers
(6) toxin-induced skin ulcers
(7) other
Causes of vasculitis:
(1) Wegener's granulomatosis
(2) polyarteritis nodosa (PAN)
(3) cryoglobulinemia (as vasculitis or occlusive)
(4) Takayasu's vascultiis
(5) leukocytoclastic vasculitis
(6) drug-induced lupus
Conditions with vascular occlusions:
(1) antiphospholipid antibody
(2) livedoid vasculopathy
(3) venous stasis ulceration
(4) small vessel occlusive arterial disease
(5) Klippel-Trenaunay-Weber syndrome
Hematologic malignancies:
(1) T cell lymphoma (angiocentric, anaplastic large cell, Mycosis fungoides)
(2) leukemia cutis
(3) Langerhans cell histiocytosis
Skin infection:
(1) fungal infection
(2) herpes simplex virus
(3) mycobacterial infection
(4) amebiasis cutis
(5) Pseudomonas aeruginosa or other Gram negative bacteremia
Drug-induced skin ulcers:
(1) hydroxyurea
Toxin-induced skin ulcers:
(1) bromoderma
(2) spider bites (brown recluse spider)
Miscellaneous:
(1) ulcerating necrobiosis lipoidica
(2) cutaneous Crohn's disease
(3) Munchausen's syndrome or other factitious disorder
(4) injection site reaction
(5) contact vulvitis
