A variety of conditions may compress or entrap the posterior interosseous nerve at or near the supinator muscle in the proximal forearm. This can result in signs and symptoms in the distribution of the radial nerve.


Synonym: deep radial nerve syndrome


Conditions that may cause the posterior interosseous nerve syndrome:

(1) congenital fibrous adhesion between the brachioradialis and brachialis muscles (arcade of Frohse)

(2) fibrous tissue at the anterior radiohumeral joint capsule

(3) abnormal proliferation of blood vessels adjacent to the nerve

(4) intermuscular septum between the extensor digitorum minimi and extensor carpi ulnaris muscles

(5) fibrous tissue at the distal margin of the supinator muscle

(6) overuse injury in athletes or musicians (? related to muscle hypertrophy)

(7) use of crutches or other mechanical external compression

(8) fracture of the radial head

(9) lipoma or other soft tissue tumor adjacent to the nerve

(10) benign cyst adjacent to the nerve

(11) septic arthritis at the elbow

(12) rheumatoid synovitis at the elbow

(13) synovial chondromatosis at the elbow


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