A lupus anticoagulant may be encountered in a wide range of patients. Sometimes it is clinically significant and sometimes the finding is incidental.


Conditions associated with the lupus anticoagulant:

(1) systemic lupus erythematosus (SLE)

(2) other autoimmune disease (rheumatoid arthritis, Sjogren's MCTD, etc)

(3) viral infection, including HIV

(4) other infections (malaria, tuberculosis, etc)

(5) drugs (procainamide, quinidine, neuroleptics, phenytoin, other)

(6) familial

(7) normal and asymptomatic


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