A number of conditions may be complicated by disseminated intravascular coagulation (DIC). Identifying the cause of DIC is important in the management of a patient.
Infection:
(1) sepsis
(2) other severe infection
Hematopoietic malignancy:
(1) acute promyelocytic leukemia (APML)
(2) acute leukemia
(3) malignant lymphoma
(4) myeloproliferative neoplasm
Tumor:
(1) solid malignancy (especially if metastatic)
(2) vascular tumor
Tissue damage:
(1) burn
(2) trauma (including fat embolism)
(3) heat stroke
(4) rhabdomyolysis
(5) surgery
(6) neurotrauma
Vascular disease:
(1) aortic aneurysm
(2) giant hemangioma
(3) vasculitis
Organ disease:
(1) liver disease
(2) acute pancreatitis
Shock
Hemolytic transfusion reaction
Snake bite
Hypothermia
Obstetrical:
(1) amniotic fluid embolism
(2) placental abruption
(3) pre-eclampsia
Transplant rejection
Drugs of abuse (amphetamine, cocaine, other)
Other
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