Collapsing glomerulopathy may be primary or secondary. Control of secondary causes may be associated with reversal of the condition.
Infections associated with collapsing glomerulopathy:
(1) HIV-associated nephropathy
(2) Parvovirus B19
(3) cytomegalovirus
(4) tuberculosis
(5) hepatitis B
(6) coxsackievirus
(7) malaria
(8) Epstein-Barr virus
(9) other parasitic diseases
Immune disorders associated with collapsing glomerulopathy:
(1) renal allograft with microvascular injury or graft failure
(2) adult onset Still's disease
(3) light chain amyloidosis
(4) SLE
(5) myeloma
Diseases associated with collapsing glomerulopathy:
(1) sickle cell disease
(2) atheroembolic disease
(3) hemophagocytic syndrome
(4) thrombotic microangiopathy
(5) diabetes
(6) familial collapsing glomerulopathy
Other conditions associated with collapsing glomerulopathy:
(1) intravenous drug abuse
(2) medications (pamidronate, anthracycline, interferon)
(3) hydrophilic polymer emboli
It can also occur as a primary (idiopathic) disease without obvious inciting cause.
