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Composite Laryngeal Recurrence Staging System (CLRSS) of Lacy and Piccirillo for Recurrent Laryngeal Squamous Cell Carcinoma

Description

Lacy and Piccirillo developed a staging system for evaluating patients with recurrent squamous cell carcinoma of the larynx. This Composite Laryngeal Recurrence Staging System (CLRSS) correlates with survival and can identify patients who may benefit from more aggressive therapy. The author are from Royal Victorian Eye and Ear Hospital in Victoria, Australia, and Washington University in St. Louis.


 

Patient selection:

(1) squamous cell carcinoma of the larynx

(2) tumor free after initial treatment for > 2 months (else considered persistent disease)

 

Parameters:

(1) original TNM stage

(2) extent of recurrence (local, regional or distant)

 

Definitions for recurrence:

(1) local: within or immediately adjacent to original tumor site

(2) regional: nonlocal recurrence within the neck

(3) distant: metastases outside of the neck

TNM Stage

Extent of Recurrence

Stage

I

local

I

I

regional

I

II

local

II

III

local

II

II

regional

III

III

regional

III

all other combinations

IV

 

 

CLRSS Stage

Probability of 2 Year Survival

I

67%

II

56%

III

39%

IV

13%

 


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