Description

Giraldez et al developed a composite laboratory index (LI) which provides prognostic information that is complemetary to the TIMI Risk Score. The index can help to identify patients who may require more aggressive management. The authors are from Brigham and Women's Hospital and Harvard Medical School in Boston.


 

Parameters:

(1) hemoglobin in g/dL

(2) creatinine clearance in mL per min (derived with the Cockcroft and Gault equation)

 

laboratory index =

= (15 - (hemoglobin)) + ((100 - (creatinine clearance)) / 8)

 

Interpretation:

• minimum index: < 0 (with high hemoglobin)

• maximum score: > 20

• The higher the index the greater the mortality.

Laboratory Index

30 Day Mortality Rate

< 0.5

1.8%

0.5 to 1.99

2.1%

2.0 to 3.49

4.3%

3.5 to 4.99

5.9%

5.0 to 6.99

7.9%

>= 7.00

17.6%

 

The index can be used in conjunction with the TIMI risk score to predict the mo

 

Laboratory Index

TIMI Risk Score

30 Day Mortality Rate

< 2.0

< 2

1%

 

3 to 4

3%

 

> 4

10%

2.0 to 4.99

< 2

2.5%

 

3 to 4

6%

 

> 4

15%

>= 5.0

< 2

4%

 

3 to 4

10%

 

> 4

22%

 


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