Rule et al developed a series of equations for estimating the glomerular filtration rate for a patient with chronic kidney disease. One was a composite score that combined the results of separate GFR estimates based on serum creatinine and cystatin C. The authors are from the Mayo Clinic in Rochester, Minnesota.



(1) estimated GFR based on age, gender and serum creatinine concentration (see previous section)

(2) estimated GFR based on serum cystatin C concentration


composite estimate for the GFR in mL per min per square meter BSA =

= SQRT((estimated GFR based on serum creatinine)*(estimated GFR based on serum cystatin C))


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