Organism: Salmonella enterica serotype typhi
Complications:
(1) hepatitis with elevated liver function tests
(2) cholecystitis
(3) myocarditis
(4) meningitis
(5) confusion, agitation, delirium or psychosis
(6) bronchitis or pneumonia
(7) pharyngitis
(8) miscarriage or neonatal typhoid (if pregnant female)
(9) abscess
(10) DIC (usually subclinical and rarely clinically significant)
(11) seizure activity in small children under 5 years of age
Organ failures associated with severe disease:
(1) gastrointestinal perforation with peritonitis
(2) gastrointestinal hemorrhage, which may be massive
(3) shock
(4) encephalopathy
Other problems:
(1) relapse
(2) reinfection
(3) chronic carrier state ("Typhoid Mary", which may be more common in patients with cholelithiasis or schistosomiasis)
