Sites posing problems for proper care:
(1) finger and toes
(2) external genitalia (penis, scrotum, labia)
(3) facial structures (eyelid, nose, tongue and ear)
Potential complications at the injection sites:
(1) compartment syndrome if space available for expansion is limited and too much immunoglobulin is injected
(2) pain, especially around a fingernail or toenail
(3) secondary infection
(4) allergic reaction to vaccine component
The risk of treatment failure is increased if:
(1) insufficient immunoglobulin is injected
(2) injection of immunoglobulin is delayed
(3) the wound is sutured early. Suturing is delayed whenever possible.
(4) direct inoculation into a nerve
Problems associated with local injection are minimized when done by a well-trained and experienced staff.