The presence of the pseudoexfoliation (PEX) syndrome may increase the risk of complications during and following cataract surgery.


Pseudoexfoliation syndrome is the presence of fibrillogranular deposits on the anterior lens capsule and at the papillary margin seen during a slit-lamp examination.


It is associated with dysfunction of the blood-aqueous barrier and increased protein in the aqueous fluid.


Complications following cataract surgery include:

(1) secondary cataract (risk lower in diabetic patients)

(2) rapidly progessive open angle glaucoma

(3) cilo-lenticular angle closure glaucoma

(4) corneal decompensation

(5) luxation or subluxation of the intra-ocular lens

(6) inflammation with fibrin deposition

(7) poor papillary dilatation


A patient with the pseudoexfoliation syndrome should be informed of the risks prior to cataract surgery. Steps should be taken during and after surgery to reduce factors that may contribute to complications.


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