The nevus of Ota may be associated with a number of complications, some of which are life-threatening. These require regular monitoring of the affected patient.
Complications:
(1) glaucoma
(2) malignant melanoma: dermal, uveal, retroorbital, optic nerve, meningeal
(3) other melanocytic proliferations (giant blue nevus)
(4) cosmetic appearance
Signs of malignant transformation on MRI:
(1) fast-growing mass
(2) changing pattern of signal intensities
(3) infiltration of adjacent structures
In addition to regular surveillance the patient should be instructed to report the onset of any new symptoms and change in existing ones.
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