Comparison of the Different Meningococcal Predictive Instruments

age

x

sex

antibiotics preadmission

x

fever, temperature

x

temperature difference

x

petechiae < 12 hours

x

x

petechiae, extensive

x

purpura

x

absence of meningism

x

focal neurologic signs

x

disturbed consciousness, altered mental state

x

coma

x

hypotension or shock

x

x

x

clinical deterioration

x

vasoconstriction

hyperventilation or cyanosis

WBC in CSF

x

x

WBC in blood

x

x

thrombocytopenia

x

hypofibrinogenemia

decreased factor V

DIC or coagulopathy

x

bicarbonate

base excess or deficit

x

metabolic acidosis

glucose

potassium

serum antigen

erythrocyte sedimentation rate

x

C reactive protein

diarrhea

tachycardia

oliguria

age

x

sex

antibiotics preadmission

fever, temperature

x

temperature difference

petechiae < 12 hours

petechiae, extensive

x

purpura

(x)

absence of meningism

x

x

focal neurologic signs

disturbed consciousness, altered mental state

x

coma

x

(x)

hypotension or shock

(x)

x

clinical deterioration

vasoconstriction

(x)

x

hyperventilation or cyanosis

x

WBC in CSF

x

WBC in blood

x

x

thrombocytopenia

x

(x)

x

hypofibrinogenemia

x

decreased factor V

DIC or coagulopathy

x

x

bicarbonate

(x)

base excess or deficit

metabolic acidosis

glucose

potassium

x

serum antigen

erythrocyte sedimentation rate

C reactive protein

diarrhea

tachycardia

oliguria

age

sex

antibiotics preadmission

fever, temperature

x

temperature difference

petechiae < 12 hours

x

petechiae, extensive

x

purpura

absence of meningism

(x)

focal neurologic signs

disturbed consciousness, altered mental state

x

coma

x

x

hypotension or shock

x

x

x

x

clinical deterioration

vasoconstriction

hyperventilation or cyanosis

WBC in CSF

(x)

WBC in blood

x

x

thrombocytopenia

x

hypofibrinogenemia

decreased factor V

DIC or coagulopathy

x

bicarbonate

base excess or deficit

metabolic acidosis

x

glucose

potassium

serum antigen

x

erythrocyte sedimentation rate

C reactive protein

diarrhea

tachycardia

oliguria

age

sex

x

antibiotics preadmission

fever, temperature

x

temperature difference

petechiae < 12 hours

petechiae, extensive

x

purpura

(x)

x

absence of meningism

focal neurologic signs

disturbed consciousness, altered mental state

x

(x)

coma

(x)

x

hypotension or shock

x

(x)

clinical deterioration

vasoconstriction

hyperventilation or cyanosis

WBC in CSF

x

x

WBC in blood

x

x

thrombocytopenia

x

x

x

hypofibrinogenemia

x

decreased factor V

x

DIC or coagulopathy

x

bicarbonate

base excess or deficit

x

x

metabolic acidosis

glucose

x

potassium

x

serum antigen

erythrocyte sedimentation rate

C reactive protein

x

diarrhea

tachycardia

oliguria

age

x

sex

antibiotics preadmission

fever, temperature

x

temperature difference

petechiae < 12 hours

duration

petechiae, extensive

purpura

x

x

absence of meningism

x

x

focal neurologic signs

x

disturbed consciousness, altered mental state

coma

x

hypotension or shock

x

x

x

x

clinical deterioration

vasoconstriction

cold extremities

hyperventilation or cyanosis

x

x

WBC in CSF

WBC in blood

x

thrombocytopenia

hypofibrinogenemia

decreased factor V

DIC or coagulopathy

x

bicarbonate

base excess or deficit

x

x

metabolic acidosis

glucose

potassium

serum antigen

erythrocyte sedimentation rate

C reactive protein

diarrhea

x

tachycardia

x

oliguria

x

age

sex

antibiotics preadmission

fever, temperature

temperature difference

petechiae < 12 hours

petechiae, extensive

purpura

absence of meningism

focal neurologic signs

disturbed consciousness, altered mental state

coma

hypotension or shock

x

clinical deterioration

vasoconstriction

x

hyperventilation or cyanosis

WBC in CSF

WBC in blood

x

thrombocytopenia

x

x

hypofibrinogenemia

x

decreased factor V

DIC or coagulopathy

bicarbonate

base excess or deficit

x

metabolic acidosis

glucose

potassium

serum antigen

erythrocyte sedimentation rate

C reactive protein

diarrhea

tachycardia

oliguria