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Comparing DNA Restriction Fragment Patterns in a Pulse Field Gel Electrophoresis (PFGE)

Specialty:

Clinical Laboratory

Objective:

ICD-10:

Description:

Restriction enzymes cut a DNA strand at specific places, resulting in multiple fragments. These can be separated into different sizes by pulse-field gel electrophoresis (PFGE) to generate a "fingerprint" for the DNA. DNA from related bacterial isolates may differ slightly due to genetic differences.

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