Lasalvia et al reported a comorbidity score for patients with cancer. It was developed for use in patients with COVID-19 but can be used in other situations. The authors are from IRCCS Istituto Nazionale dei Tumori (Milan) and the University of Milano-Bicocca in Italy.
Patient selection: cancer
Parameters:
(1) coronary and peripheral artery disease
(2) anemia (autoimmune hemolytic, other)
(3) chronic pain
(4) hypertension
(5) chronic lung disease (COPD, asthma, other)
(6) other diseases of the digestive system
(7) ill-defined condition with signs and symptoms
(8) other diseases of the respiratory tract
(9) other diseases of the genitourinary tract
(10) oral anticoagulant therapy
(11) diabetes without insulin therapy
(12) gout
(13) hypothyroidism
(14) ischemic heart disease or angina
(15) infection (tuberculosis, other)
(16) other diseases of the musculoskeletal system and connective tissue
(17) glaucoma
(18) heart failure
(19) other kidney disorders
(20) other disorders of the nervous system and sense organs (eyes, ears, smell)
(21) other disorders of endocrine, nutritional, and metabolic diseases
|
Parameter |
Finding |
Points |
|
CAD and PAD |
no |
0 |
|
|
yes |
1 |
|
anemia |
no |
0 |
|
|
yes |
1 |
|
chronic pain |
no |
0 |
|
|
yes |
-1 |
|
hypertension |
no |
0 |
|
|
yes |
1 |
|
chronic respiratory disease |
no |
0 |
|
|
yes |
-2 |
|
other diseases GI system |
no |
0 |
|
|
yes |
-2 |
|
ill-defined condition |
no |
0 |
|
|
yes |
-2 |
|
other respiratory disease |
no |
0 |
|
|
yes |
16 |
|
other GU disorder |
no |
0 |
|
|
yes |
1 |
|
oral anticoagulant therapy |
no |
0 |
|
|
yes |
2 |
|
diabetes without insulin |
no |
0 |
|
|
yes |
1 |
|
gout |
no |
0 |
|
|
yes |
1 |
|
hypothyroidism |
no |
0 |
|
|
yes |
-1 |
|
ischemic heart disease, angina |
no |
0 |
|
|
yes |
1 |
|
infectious disease |
no |
0 |
|
|
yes |
1 |
|
musculoskeletal disease |
no |
0 |
|
|
yes |
1 |
|
glaucoma |
no |
0 |
|
|
yes |
2 |
|
heart failure |
no |
0 |
|
|
yes |
-3 |
|
other kidney disorder |
no |
0 |
|
|
yes |
1 |
|
other disorder of CNS, ear or eyes |
no |
0 |
|
|
yes |
3 |
|
other endocrine. metabolic or nutritional disorder |
no |
0 |
|
|
yes |
2 |
where:
• Assuming that coronary and peripheral vascular disease implies the presence of both.
• Diabetes treated with insulin is not states specifically but would be covered by the other disorders of endocrine/nutritional/metabolic.
• The 16 points for other disorders of the respiratory system is different from other factors.
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: -11
• maximum score: 35
|
Score |
Class |
|
<= -1 |
1 |
|
0 |
2 |
|
1 |
3 |
|
2, 3 or 4 |
4 |
|
>= 5 |
|
Performance:
• The area under the ROC curve is 0.85.
