Description

Zhang et al combined the Fibrinogen-to-Prealbumin Ratio (FPR) and Prognostic Nutritional Index (PNI) to evaluate gastric cancer patients following surgery. The authors are from Nontong University and associated hospitals in China.


Parameters:

(1) plasma fibrinogen (units not given. presumed g/L)

(2) serum prealbumin (transthyretin, units not given, may be mg/dL to get reported ratio)

(3) serum albumin in g/L

(4) absolute lymphocyte count in 10^9/L

 

fibrinogen to prealbumin ratio =

= (fibrinogen) / (prealbumin)

 

prognostic nutritional index =

= (albumin) + (5 * (absolute lymphocyte count))

 

FPR

PNI

Score for FPR-PNI

< 0.1036

>= 48.525

0

< 0.1036

< 48.525

1

>= 0.1036

>= 48.525

1

>= 0.1036

< 48.525

2

 

 

Score for FPR-PNI

5-Year Overall Survival < 60 Years

5-Year Overall Survival >= 60 Years

0

19%

27%

1

41%

48%

2

72%

65%

from Figure 3

 

Performance:

The area under the ROC curve is 0.74 for a patient >= 60 years.

The area under the ROC curve is 0.62 for a patient < 60 years.


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