Patient selection: age >= 18 years, sepsis, on general ward for > 24 hours, systolic blood pressure < 90 mm Hg
Criteria for ICU transfer - one or more of the following:
(1) sustained shock requiring vasopressors
(2) acute respiratory failure
(3) acute heart failure or pulmonary edema
(4) acute renal failure requiring hemodialysis
(5) drowsy (altered mental status)
Cut-off values for ICU transfer:
(1) MEWS >= 5.5 (MEWS range 0 to 14; a score >= 5 is usual trigger; since the score is an integer the cut-off needs to be 5 or 6))
(2) blood lactate concentration >= 3.05 mmol/L
Performance:
• The area under the ROC curve is 0.9.
