Description

A collider is a variable that arises independently from a cause and a purported effect.


Collider bias:

(1) can arise during study design or statistical analysis

(2) can indicate an association between the cause and effect when none exists, or distort the association if one exists

 

Alternative terms:

(1) selection bias in sampling

(2) admission rate bias (2 conditions that can cause a patient to be hospitalized may appear to be related if a study is performed on hospitalized patients)

 

Related biases:

(1) confounder bias: the confounder can cause both the exposure and the outcome

 

The phenomenon can be visualized by the use of a causal diagram (directed acyclic graph or DAG).

 

Collider bias can be prevented through proper use of inclusion criteria. Exposure and outcome should not drive inclusion or selective retention of subjects.


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