Coats Disease is an idiopathic condition associated with a congenital retinal telangiectasia.
Clinical features:
(1) It tends to occur in young males.
(2) It presents withunilateral visual changes (flashes, floaters, visual loss).
(3) There is a congenital retinal telangiectasia (angiomatous proliferation), with abnormal retinal blood vessels.
(4) There is development of intraretinal and subretinal exudates.
(5) There is no evidence of significant retinal or vitreal traction.
(6) This results in a progressive exudative retinal detachment.
Complications:
(1) rubeosis iridis and neovascular glaucoma
(2) severe vision loss
(3) variable macular fibrosis
Management:
(1) ablative therapy of telangiectatic vessels
(2) anti-VEGF agents
Differential diagnosis:
(1) retinoblastoma
